CYCLE MOBILITY IN 1,4-DIHYDROPYRIDINE AND ITS MONOALKYL AND PHENYL DERIVATIVES

被引：8

作者：

SHISHKIN, OV ^{[1
]}

TIMOFEEVA, TV ^{[1
]}

DESENKO, SM ^{[1
]}

ORLOV, VD ^{[1
]}

LINDEMAN, SV ^{[1
]}

STRUCHKOV, YT ^{[1
]}

机构：

[1] AN NESMEYANOV ORGANOELEMENT CPDS INST,117813 MOSCOW,RUSSIA

来源：

RUSSIAN CHEMICAL BULLETIN | 1993年 / 42卷 / 07期

关键词：

1,4-DIHYDROPYRIDINE; MOLECULAR MECHANICS; CONFORMATIONAL ANALYSIS;

D O I：

10.1007/BF00701996

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The conformational mobility of the 1,4-dihydropyridine cycle has been studied by the molecular mechanics method. It was shown that the N(1) and C(4) atoms are displaced asymmetrically from the plane of the double bonds. The asymmetry is the result of conjugation between the nitrogen lone pair and the pi systems of the double bonds. The influence of alkyl and phenyl substituents at the carbon atoms on the equilibrium conformation and cycle mobility has been investigated.

引用

页码：1160 / 1162

页数：3

共 10 条

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