ON CARCINOGENIC ACTIVITY OF AMINO-PHENANTHRENES AND THEIR DERIVATIVES

被引:4
作者
DANNENBERG, H
HUGGINS, C
机构
[1] The Ben May Laboratory for Cancer Research, The University of Chicago, Chicago
来源
ZEITSCHRIFT FUR KREBSFORSCHUNG | 1969年 / 72卷 / 04期
关键词
D O I
10.1007/BF00525803
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1-, 2-, 3- and 9-Aminophenanthrenes produce mammary cancer with approximately the same activity when fed to female Sprague-Dawley rats. Among the corresponding acetamines only 2-acetaminophenanthrene is active. 2-, 3- and 9-Aminophenanthrene-N-dipropylphosphates are inactive. - Among the above mentioned compounds only 3- and 9-acetaminophenanthrene show a weak activity when injected into mice of CF-1-strain. The duration of the experiment was 250 days. © 1969 Springer-Verlag.
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页码:321 / +
页数:1
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