THE USE OF MASS-SPECTROMETRY IN THE STUDY OF CHEMICALLY-REACTIVE DRUG METABOLITES - APPLICATION OF MS/MS AND LC/MS TO THE ANALYSIS OF GLUTATHIONE-LINKED AND RELATED S-LINKED CONJUGATES OF N-METHYLFORMAMIDE

被引：34

作者：

BAILLIE, TA

PEARSON, PG

RASHED, MS

HOWALD, WN

机构：

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1989年 / 7卷 / 12期

关键词：

D O I：

10.1016/0731-7085(89)80140-2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：1351 / 1360

页数：10

共 20 条

[1]

BAILLIE TA, 1981, PHARMACOL REV, V33, P81

[2] BIOCHEMICAL-MECHANISMS IN CHEMICAL-INDUCED LUNG INJURY - ROLES OF METABOLIC-ACTIVATION [J].

BOYD, MR .

CRC CRITICAL REVIEWS IN TOXICOLOGY, 1980, 7 (02) :103-176

[3] CONTINUOUS-FLOW SAMPLE PROBE FOR FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY [J].

CAPRIOLI, RM ;

FAN, T ;

COTTRELL, JS .

ANALYTICAL CHEMISTRY, 1986, 58 (14) :2949-2954

[4]

Chasseaud L.F., 1976, GLUTATHIONE METABOLI, P77

[5] FORMATION OF S-[2-(N-7-GUANYL)ETHYL] ADDUCTS BY THE POSTULATED S-(2-CHLOROETHYL)CYSTEINYL AND S-(2-CHLOROETHYL)GLUTATHIONYL CONJUGATES OF 1,2-DICHLOROETHANE [J].

FOUREMAN, GL ;

REED, DJ .

BIOCHEMISTRY, 1987, 26 (07) :2028-2033

[6] CHARACTERIZATION OF GLUTATHIONE CONJUGATES BY FAST ATOM BOMBARDMENT TANDEM MASS-SPECTROMETRY [J].

HAROLDSEN, PE ;

REILLY, MH ;

HUGHES, H ;

GASKELL, SJ ;

PORTER, CJ .

BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1988, 15 (11) :615-621

[7] THE USE OF ALKOXYCARBONYL DERIVATIVES FOR THE MASS-SPECTRAL ANALYSIS OF DRUG THIOETHER METABOLITES - STUDIES WITH THE CYSTEINE, MERCAPTURIC ACID AND GLUTATHIONE CONJUGATES OF ACETAMINOPHEN [J].

HOFFMANN, KJ ;

BAILLIE, TA .

BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1988, 15 (12) :637-647

[8]

JAKOBY WB, 1980, ENZYMATIC BASIS DETO, V2, P63

[9]

KESTELL P, 1986, BIOCHEM PHARMACOL, V35, P2283, DOI 10.1016/0006-2952(86)90452-1

[10]

Larsson A., 1983, FUNCTIONS GLUTATHION

← 1 2 →