RELEVANCE OF BROAD-SPECTRUM AND FUNGICIDAL ACTIVITY OF ANTIFUNGALS IN THE TREATMENT OF DERMATOMYCOSES

被引:68
作者
CLAYTON, YM
机构
[1] St John's Institute of Dermatology, St Thomas' Hospital, London
关键词
D O I
10.1111/j.1365-2133.1994.tb06084.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The in vitro fungistatic and fungicidal activities of terbinafine, amorolfine and itraconazole against dermatophytes were compared. All three compounds showed very good activity against all dermatophyte species tested, but only terbinafine and amorolfine exhibited primary fungicidal activity. These two compounds were also active in vitro against other filamentous fungi which cause onychomycoses, such as Scytalidium and Scopulariopsis species.
引用
收藏
页码:7 / 8
页数:2
相关论文
共 5 条
[1]  
ODDS FC, 1985, SEMIN DERMATOL, V4, P260
[2]   ANTIFUNGAL ACTIVITY OF THE ALLYLAMINE DERIVATIVE TERBINAFINE INVITRO [J].
PETRANYI, G ;
MEINGASSNER, JG ;
MIETH, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (09) :1365-1368
[3]   PRECLINICAL DATA AND MODE OF ACTION OF AMOROLFINE [J].
POLAK, A .
DERMATOLOGY, 1992, 184 :3-7
[4]  
SHADOMY S, 1985, SABOURAUDIA, V23, P125
[5]   THE INVITRO ANTIFUNGAL SPECTRUM OF ITRACONAZOLE [J].
VANCUTSEM, J .
MYCOSES, 1989, 32 :7-13