AUTOLYSIS AND SECONDARY GROWTH OF MYCOBACTERIUM TUBERCULOSIS IN SUBMERGED CULTURE

被引:54
作者
WAYNE, LG
DIAZ, GA
机构
关键词
D O I
10.1128/JB.93.4.1374-1381.1967
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Mycobacterium tuberculosis has been found to exhibit autolysis and spontaneous secondary growth in modified Sauton Medium. The phenomenon is a function of high glycerol concentration of the medium and limitation of air in test tubes. It is not a function of depletion of nutrients and is probably not a manifestation of lysogeny or spheroplast formation. The cycle of growth, autolysis, and secondary growth is related to development of lethal conditions during a period of severe oxygen limitation followed by a metabolic change associated with slower depletion of glycerol.
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页码:1374 / +
页数:1
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