ENDOSCOPIC SCLEROSIS OF THE GASTRIC CARDIA FOR PREVENTION OF EXPERIMENTAL GASTROESOPHAGEAL REFLUX

被引：23

作者：

DONAHUE, PE ^{[1
]}

CARVALHO, PJPC ^{[1
]}

DAVIS, PE ^{[1
]}

SHEN, YJE ^{[1
]}

MIIDLA, I ^{[1
]}

BOMBECK, CT ^{[1
]}

NYHUS, LM ^{[1
]}

机构：

[1] VET ADM W SIDE MED CTR,CHICAGO,IL 60680

来源：

GASTROINTESTINAL ENDOSCOPY | 1990年 / 36卷 / 03期

关键词：

D O I：

10.1016/S0016-5107(90)71017-6

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Surgical anti-reflux therapy appears to involve the muscles of the proximal gastric cardia and those of the lower esophageal sphincter. In an experimental canine reflux model, we injected sclerosant solution into the submucosa of the proximal gastric cardia, hypothesizing that the subsequent fibrotic reaction might exert an anti-reflux effect Reflux was induced by atropine infusion, and the amount of reflux was quantitated by pH monitoring. Endoscopic sclerosis was effective in preventing reflux induced by high-dose atropine. Because the length and pressure of the lower esophageal sphincter were unaffected by endoscopic treatment, reflux prevention was possibly related to enhancement of the gastric component of the reflux barrier. © 1990, American Society for Gastrointestinal Endoscopy. All rights reserved.

引用

页码：253 / 256

页数：4

共 15 条

[1] ACHALASIA OF THE ESOPHAGUS - TREATMENT CONTROVERSIES AND THE METHOD OF CHOICE [J].