CHEMOENZYMATIC SYNTHESIS OF A GLYCOSPHINGOLIPID

被引：15

作者：

GUILBERT, B ^{[1
]}

KHAN, TH ^{[1
]}

FLITSCH, SL ^{[1
]}

机构：

[1] DYSON PERRINS LAB,S PARKS RD,OXFORD OX1 3QY,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 20期

关键词：

D O I：

10.1039/c39920001526

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The novel glycosphingolipid 7 is synthesised by two successive enzymatic glycosylation steps from 5 using a beta(1-4)-galactosyl transferase and an alpha(2-6)-sialyl transferase, both of which are commercially available.

引用

页码：1526 / 1527

页数：2

共 21 条

[1] ENZYMIC-SYNTHESIS OF THE SIALYLGLYCOPEPTIDE, ALPHA-D-NEUPAC-(2-]6)-BETA-D-GALP-(1-]4)-BETA-D-GLCPNAC-(1-]4N)-L-ASN [J].

AUGE, C ;

GAUTHERON, C ;

PORA, H .

CARBOHYDRATE RESEARCH, 1989, 193 :288-293

[2]

BASU S C, 1991, Glycobiology, V1, P469, DOI 10.1093/glycob/1.5.469

[3]

BOUHOURS D, 1991, J BIOL CHEM, V266, P12944

[4] APPLICATION OF TRICHLORACETAMIDE PROCESSES TO 2-DEOXY-2-PHTHALIMIDO-D-GLUCOSE DERIVATIVES - SYNTHESIS OF OLIGOSACCHARIDES OF THE CORE REGION OF ORTHO-GLYCOPROTEINS OF MUCINE TYPE [J].

GRUNDLER, G ;

SCHMIDT, RR .

CARBOHYDRATE RESEARCH, 1985, 135 (02) :203-218

[5]

HANAI N, 1988, J BIOL CHEM, V263, P10915

[6]

KANFER JN, 1983, HDB LIPID RES SPHING, V3, P89

[7]

Lemieux R. U., 1976, ACS SYM SER, V39, P90, DOI DOI 10.1021/BK-1977-0039.CH006

[8] THE USE OF PORCINE LIVER (2-]3)-ALPHA-SIALYLTRANSFERASE IN THE LARGE-SCALE SYNTHESIS OF ALPHA-NEUP5AC-(2-]3)-BETA-D-GALP-(1-]3)-D-GLCPNAC, THE EPITOPE OF THE TUMOR-ASSOCIATED CARBOHYDRATE ANTIGEN CA-50 [J].

LUBINEAU, A ;

AUGE, C ;

FRANCOIS, P .

CARBOHYDRATE RESEARCH, 1992, 228 (01) :137-144

[9] A QUANTITATIVE METHOD FOR SEPARATING REACTION COMPONENTS OF CMP-SIALIC ACID - LACTOSYLCERAMIDE SIALYLTRANSFERASE USING SEP PAK C-18 CARTRIDGES [J].

MELKERSONWATSON, LJ ;

KANEMITSU, K ;

SWEELEY, CC .

GLYCOCONJUGATE JOURNAL, 1987, 4 (01) :7-16

[10]

NOJIRI H, 1991, J BIOL CHEM, V266, P4531

← 1 2 3 →