CLINICOPATHOLOGICAL CORRELATION OF CHOROIDAL NEOVASCULARIZATION DEMONSTRATED BY INDOCYANINE GREEN ANGIOGRAPHY IN A PATIENT WITH RETENTION OF GOOD VISION FOR ALMOST 4 YEARS

被引：94

作者：

CHANG, TS ^{[1
]}

FREUND, KB ^{[1
]}

DELACRUZ, Z ^{[1
]}

YANNUZZI, LA ^{[1
]}

GREEN, WR ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV HOSP,EYE PATHOL LAB,600 N WOLFE ST,BALTIMORE,MD 21287

来源：

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 1994年 / 14卷 / 02期

关键词：

AGE-RELATED MACULAR DEGENERATION; BASAL LAMINAR DEPOSIT; CHOROIDAL NEOVASCULAR MEMBRANE; CHOROIDAL NEOVASCULARIZATION; CLINICOPATHOLOGICAL CORRELATION; FLUORESCEIN ANGIOGRAPHY; INDOCYANINE GREEN (ICG) ANGIOGRAPHY; OCCULT CHOROIDAL NEOVASCULARIZATION;

D O I：

10.1097/00006982-199414020-00004

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Objective: The clinicopathologic features of age-related macular degeneration (AMD) with occult choroidal neovascularization (CNV) detected by digital indocyanine green (ICG) videoangiography in an 82-year-old woman are discussed. Methods: Serial sections through the macula of both eyes were prepared, and two-dimensional reconstruction maps depicting the histopathologic features were drawn. A technique by which electron microscopic examination of sections removed from glass slides was performed is described. Result: Histopathologic examination of the lesion disclosed a 3.5 mm x 0.02 mm thick fibrovascular subretinal pigment epithelial choroidal neovascular membrane in an eye with diffuse basal laminar deposit in the macula. Conclusion: This case represents the first clinicopathologic correlation involving ICG videoangiography of CNV. The findings support the growing clinical impression that ICG videoangiography is of value in identifying what has been previously described as ill-defined or occult CNV.

引用

页码：114 / 124

页数：11

共 18 条

[1] Flower R.W., Hochheimer B.F., Clinical infrared absorption angiography of the choroid, Am J Ophthalmol, 73, pp. 458-459, (1972)
[2] Flower R.W., Hochheimer B.F., A clinical technique and apparatus for simultaneous angiography of the separate retinal and choroidal circulation, Invest Ophthalmol Vis Sci, 12, pp. 248-261, (1973)
[3] Hochheimer B.F., D'Anna S.A., Angiography with new dyes, Exp Eye Res, 27, pp. 1-16, (1978)
[4] Schneider A., Koboth A., Neuhauser L., Detection of subretinal neovascular membranes with indocyanine green and an infrared scanning laser ophthalmoscope, Am J Ophthalmol, 113, pp. 45-51, (1992)
[5] Hayashi K., Hasegawa Y., Tazawa Y., Et al., Clinical application ofindocyanine green angiography to choroidal neovascularization, Jpn J Ophthalmol, 33, pp. 57-65, (1989)
[6] Yannuzzi L.A., Slakter J.S., Sorenson J.A., Et al., Digital indocyanine green videoangiography and choroidal neovascularization, Retina, 12, pp. 191-223, (1992)
[7] Guyer D.R., Puliafito C.A., Mones J.M., Et al., Digital indocyanine- green angiography in chorioretinal disorders, Ophthalmology, 99, pp. 287-291, (1992)
[8] Freund K.B., Yannuzzi L.A., Sorenson J.A., Age-related macular degeneration and choroidal neovascularization, Am J Ophthalmol, 115, pp. 786-791, (1993)
[9] Bressler N.M., Bressler S.B., Fine S.L., Age-related macular degeneration, Surv Ophthalmol, 32, pp. 375-413, (1988)
[10] Argon laser photocoagulation for senile macular degeneration: Results of a randomized clinical trial, Arch Ophthalmol, 100, pp. 912-918, (1982)

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