EFFECTS OF ANTIDEPRESSANT DRUGS ON WAKEFULNESS AND SLEEP IN CAT

被引：26

作者：

WALLACH, MB

WINTERS, WD

MANDELL, AJ

SPOONER, CE

机构：

[1] Brain Research Institute, Departments of Pharmacology and Psychiatry, U.C.L.A. School of Medicine, Los Angeles

来源：

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1969年 / 27卷 / 06期

关键词：

D O I：

10.1016/0013-4694(69)90068-6

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Wakefulness-sleep cycles were determined for each 24 hour period during control days and each day following the administration of various antidepressant agents; i.e., amitriptyline, desmethylimipramine and imipramine; chlorpromazine and perphenazine; pargyline; or methamphetamine. All of the agents induced an initial suppression of RPS. Methamphetamine induced an increase in total wakefulness during the suppression, whereas the other agents studied induced an increase in slow wave activity during the suppression. None of the agents induced a clear RPS rebound. The normal wake-sleep cycle reappeared in 3-4 days following the tricyclics and phenothiazines, in 4-5 days following pargyline, and in 2 days following methamphetamine. © 1969.

引用

页码：574 / &

共 9 条

[1] EFFECT OF 4 DRUGS ON SLEEP PATTERNS IN MAN [J].

HARTMANN, E .

PSYCHOPHARMACOLOGIA, 1968, 12 (04) :346-+

[2]

HARTMANN E, 1968, PSYCHOPHYSIOLOGY, V4, P390

[3]

HARTMANN E, 1968, ARCH GEN PSYCHIAT, V19, P312

[4] EFFECT OF IMIPRAMINE DESMETHYLIMIPRAMINE AND CHLORPROMAZINE ON SLEEP-WAKEFULNESS CYCLE OF CAT [J].

HISHIKAWA, Y ;

NAKAI, K ;

IDA, H ;

KANEKO, Z .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1965, 19 (05) :518-+

[5]

Hubel D. H., 1960, ARCH ITAL BIOL, V98, P171

[6]

OKUMA TERUTO, 1967, FOLIA PSYCHIAT NEUROL JAP, V21, P1

[7] CIRCADIAN SLEEP AND WAKING PATTERNS IN LABORATORY CAT [J].

STERMAN, MB ;

KNAUSS, T ;

LEHMANN, D ;

CLEMENTE, CD .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1965, 19 (05) :509-&

[8] A CORRELATION OF EEG, RETICULAR MULTIPLE UNIT ACTIVITY AND GROSS BEHAVIOR FOLLOWING VARIOUS ANTIDEPRESSANT AGENTS IN CAT .4. [J].

WALLACH, MB ;

WINTERS, WD ;

MANDELL, AJ ;

SPOONER, CE .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1969, 27 (06) :563-&

[9] CORRELATION OF RETICULAR AND COCHLEAR MULTIPLE UNIT ACTIVITY WITH AUDITORY EVOKED RESPONSES DURING WAKEFULNESS AND SLEEP .I. [J].

WINTERS, WD ;

MORI, K ;

SPOONER, CE ;

KADO, RT .

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1967, 23 (06) :539-&

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