ION-PAIR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - USE OF LOW CONCENTRATIONS OF LONG-CHAIN ALKYLBENZYLDIMETHYLAMMONIUM CHLORIDES FOR RESOLVING ANIONIC SOLUTES

被引：48

作者：

TOMLINSON, E ^{[1
]}

RILEY, CM ^{[1
]}

JEFFERIES, TM ^{[1
]}

机构：

[1] UNIV BATH,SCH PHARM & PHARMACOL,BATH BA2 7AY,SOMERSETSHIRE,ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 173卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(01)80448-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The qualitative and quantitative determination of large anionic solutes, including the drug sodium cromoglycate, by an ion-pair high-performance liquid chromatographic technique using alkylbenzyldimethylammonium chlorides as pairing ions is described. The method provides a sensitive and selective assay for the solutes examined in both simple aqueous solutions and in complex biological fluids, and requires no pre-extraction step. Retention mechanisms are discussed. © 1979.

引用

页码：89 / 100

页数：12

共 19 条

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