LIVER AND KIDNEY INJURY AFTER ADMINISTRATION OF HEMOGLOBIN CROSS-LINKED WITH BIS(3,5-DIBROMOSALICYL) FUMARATE

被引：37

作者：

SMITH, CD

SCHUSCHEREBA, ST

HESS, JR

MCKINNEY, LA

BUNCH, D

BOWMAN, PD

机构：

[1] LETTERMAN ARMY INST RES,DIV PATHOL,SAN FRANCISCO,CA 94129

[2] LETTERMAN ARMY INST RES,DIV BLOOD RES,SAN FRANCISCO,CA 94129

来源：

BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS | 1990年 / 18卷 / 02期

关键词：

D O I：

10.3109/10731199009117305

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Human hemoglobin crosslinked between the alpha chains with bis (3,5-dibromosalicyl) fumarate (DBBF-Hb) was exchange transfused in swine and the histomorphologic changes were evaluated. Following exchange, animals were euthanized and tissues were taken for light and electron microscopy at 7.5 hours and days 1, 4, 7, and 15. Consistent hepatocellular and renal epithelial cell. © 1990, Informa UK Ltd. All rights reserved.

引用

页码：251 / 261

页数：11

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