CYTOTOXIC ACTIVITY OF STAPHYLOCOCCUS-HYICUS

被引：8

作者：

ALLAKER, RP

WHITLOCK, M

LLOYD, DH

机构：

[1] Department of Veterinary Medicine and Animal Husbandry, Royal Veterinary College, North Mymms, Herts AL9 7TA, Hawkshead Lane

来源：

VETERINARY MICROBIOLOGY | 1991年 / 26卷 / 1-2期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0378-1135(91)90052-H

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Culture supernatants from a number of Staphylococcus hyicus strains caused toxic effects to both murine fibroblast and porcine keratinocyte cells in culture. The extent of cytotoxicity was shown to differ between strains and may provide an indication of strain virulence. Purification of cytotoxic activity produced by S. hyicus (strain P119) using preparative isoelectric-focussing demonstrated it to be cytolytic, haemolytic and non-proteolytic. The cytotoxin demonstrates certain properties in common with the delta haemolysin of Staphylococcus aureus.

引用

页码：161 / 166

页数：6

共 13 条

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