INCREASE IN PLASMA PRORENIN DURING THE MENSTRUAL-CYCLE OF A BILATERALLY NEPHRECTOMIZED WOMAN

被引：19

作者：

BLANKESTIJN, PJ ^{[1
]}

DERKX, FHM ^{[1
]}

VANGEELEN, JA ^{[1
]}

DEJONG, FH ^{[1
]}

SCHALEKAMP, MADH ^{[1
]}

机构：

[1] ERASMUS UNIV,HOSP DIJKZIGT,DEPT INTERNAL MED 3,3015 GD ROTTERDAM,NETHERLANDS

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1990年 / 97卷 / 11期

关键词：

D O I：

10.1111/j.1471-0528.1990.tb02479.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Summary. To investigate the origin of the prorenin peak that occurs during the normal menstrual cycle, plasma levels of prorenin, renin, oestradiol, progesterone, LH and FSH were measured serially in a nephrectomized woman having regular hacmodialysis. The prorenin peak coincided with the LH surge and preceded the rise of progesterone, whereas renin was below the detection limit during the whole cycle. These findings indicate that the rise in prorenin during the menstrual cycle is not of renal origin but is probably due to increased production by the ovary and supports the increasing evidence for the existence of a local renin‐angiotensin system in the ovary. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：1038 / 1042

页数：5

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