CHROMOSOME-11Q LOCALIZATION OF ONE OF THE 3 EXPECTED GENES FOR THE HUMAN ALPHA-3-FUCOSYLTRANSFERASES, BY SOMATIC HYBRIDIZATION

被引：29

作者：

COUILLIN, P

MOLLICONE, R

GRISARD, MC

GIBAUD, A

RAVISE, N

FEINGOLD, J

ORIOL, R

机构：

[1] FAC PHARM CHATENAY MALABRY,CNRS,TOUR D4,F-92290 CHATENAY MALABRY,FRANCE

[2] INSERM,U73,F-75005 PARIS,FRANCE

[3] INSERM,U155,F-75005 PARIS,FRANCE

来源：

CYTOGENETICS AND CELL GENETICS | 1991年 / 56卷 / 02期

关键词：

D O I：

10.1159/000133061

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Seventy-one human x mouse hybrid cell lines were used to map the locus of a human alpha-3-fucosyltransferase to 11q. The enzyme transfers fucose onto H type 2 more efficiently than onto sialyl-N-acetyllactosamine, suggesting that it is the myeloid type of alpha-3-fucosyltransferase (Mollicone et al., 1990), which makes the 3-fucosyllactosamine epitope on polymorphonuclear cells and monocytes. This epitope is also known as CD15 (Tetteroo et al., 1987).

引用

页码：108 / 111

页数：4

共 10 条

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