ELEVATED LEVELS OF THE IGG2 SUBCLASS IN SERUM FROM PATIENTS WITH A HISTORY OF DESTRUCTIVE PERIODONTAL-DISEASE - A CASE-CONTROL STUDY

被引：21

作者：

WILTON, JMA ^{[1
]}

HURST, TJ ^{[1
]}

STERNE, JAC ^{[1
]}

CAVES, J ^{[1
]}

TILLEY, C ^{[1
]}

POWELL, JR ^{[1
]}

机构：

[1] UNILEVER RES LABS,COLWORTH LAB,SHARNBROOK MK44 1LQ,BEDS,ENGLAND

来源：

JOURNAL OF CLINICAL PERIODONTOLOGY | 1992年 / 19卷 / 05期

关键词：

ADULT PERIODONTITIS; IGG SUBCLASSES; ELISA;

D O I：

10.1111/j.1600-051X.1992.tb00652.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The levels of the 4 subclasses of IgG were estimated in the serum from 35 patients with a history of chronic periodontitis and 35 matched controls. The levels of IgG2 were significantly (P < 0.019) elevated in the patients (3.756 g l-1) compared to the controls (2.882 g l-1). The data suggest that the predominant antibody response to periodontal pathogens in periodontitis may be directed against carbohydrate or glycolipid antigens.

引用

页码：318 / 321

页数：4

共 22 条

[1]

AINAMO J, 1982, INT DENT J, V32, P281

[2]

BARRETT DJ, 1986, CLIN EXP IMMUNOL, V63, P127

[3] THE PROTEIN-COMPOSITION OF GINGIVAL CREVICULAR FLUID SAMPLED FROM MALE-ADOLESCENTS WITH NO DESTRUCTIVE PERIODONTITIS - BASE-LINE DATA OF A LONGITUDINAL-STUDY [J].

CURTIS, MA ;

STERNE, JAC ;

PRICE, SJ ;

GRIFFITHS, GS ;

COULTHURST, SK ;

WILTON, JMA ;

JOHNSON, NW .

JOURNAL OF PERIODONTAL RESEARCH, 1990, 25 (01) :6-16

[4] SEROLOGICAL INVESTIGATION OF VARIOUS FORMS OF INFLAMMATORY PERIODONTITIS [J].

FARIDA, R ;

MARSH, PD ;

NEWMAN, HN ;

RULE, DC ;

IVANYI, L .

JOURNAL OF PERIODONTAL RESEARCH, 1986, 21 (04) :365-374

[5]

FRENCH M, 1986, MONOGR ALLERGY, V19, P100

[6] GENES ASSOCIATED WITH THE G2M(23) IMMUNOGLOBULIN ALLOTYPE REGULATE THE IGG SUBCLASS RESPONSES TO HEMOPHILUS-INFLUENZAE TYPE-B POLYSACCHARIDE VACCINE [J].

GRANOFF, DM ;

SUAREZ, BK ;

PANDEY, JP ;

SHACKELFORD, PG .

JOURNAL OF INFECTIOUS DISEASES, 1988, 157 (06) :1142-1149

[7]

HAMMARSTROM L, 1986, MONOGR ALLERGY, V19, P122

[8]

JEFFERIS R, 1990, CLIN EXP IMMUNOL, V81, P357

[9]

LOE H, 1963, ACTA ODONTOL SCAND, V21, P532

[10] IGG SUBCLASSES IN HUMAN PERIODONTAL-DISEASE .3. SERUM CONCENTRATIONS OF IGG SUBCLASS IMMUNOGLOBULINS AND CIRCULATING IMMUNE-COMPLEXES [J].

MACKLER, BF ;

SCHUR, P ;

WALDROP, T ;

COKER, E ;

ROSSEN, R .

JOURNAL OF DENTAL RESEARCH, 1979, 58 (07) :1701-1704

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