IMMUNOHISTOLOGIC DEMONSTRATION OF ENDOTHELIAL DISRUPTION IN ACUTE ATHETOSIS IN PREECLAMPSIA

被引：34

作者：

KHONG, TY ^{[1
]}

MOTT, C ^{[1
]}

机构：

[1] QUEEN VICTORIA HOSP,WOMENS & CHILDRENS HOSP,DEPT OBSTET & GYNAECOL,ROSE PK,SA 5067,AUSTRALIA

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1993年 / 51卷 / 03期

关键词：

ENDOTHELIUM; IMMUNOHISTOLOGY; PREECLAMPSIA; ASPIRIN; MATERNAL-FETAL BLOOD SUPPLY;

D O I：

10.1016/0028-2243(93)90034-A

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Acute atherosis is a vasculopathy described in maternal vessels in the uterus in pre-eclamptic pregnancies. We wished to document whether, and to what extent, endothelial disruption was present in acute atherosis. Using a standard streptavidin-biotin-peroxidase immunohistologic method, we found extensive endothelial disruption in 5 cases of acute atherosis. In 2 cases, there was aneurysmal formation associated with the acute atherosis and endothelial disruption in these 2 cases was focal and less extensive. All acute atherosis lesions were related to thrombosis. None of the women had taken aspirin. We suggest that studies on the maternal uteroplacental vasculature in women who have had aspirin during pregnancy should be performed.

引用

页码：193 / 197

页数：5

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