BENDING MEMBRANES TO THE TASK - STRUCTURAL INTERMEDIATES IN BILAYER FUSION

被引:131
作者
CHERNOMORDIK, LV
ZIMMERBERG, J
机构
[1] Laboratory of Theoretical and Physical Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1855, Bldg. 10, Room 10D14
关键词
D O I
10.1016/0959-440X(95)80041-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Merger of lipid bilayers plays a central role in diverse biological fusion reactions. Recent studies suggest that different membrane fusion systems, including fusion of purely lipid bilayers, involve formation of similar stalk-type intermediates - highly bent (net negative curvature) and transient lipidic connections between fusing membranes.
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页码:541 / 547
页数:7
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