SYNTHESIS OF (+/-)-PENTALENENE

被引：28

作者：

ZHAO, SK ^{[1
]}

MEHTA, G ^{[1
]}

HELQUIST, P ^{[1
]}

机构：

[1] UNIV NOTRE DAME,DEPT CHEM & BIOCHEM,NOTRE DAME,IN 46556

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)93547-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short, formal synthesis is reported for pentalenene. The key steps are copper-catalyzed 1,4-addition of isobutylmagnesium bromide to a cyclooctenone derivative, enolate alkylation with the thiocarbene complex [(eta-5-C5H5)(CO)2Fe = CHSPh]+PF6-, and cyclopentane ring formation by means of intramolecular C-H insertion, leading to a late intermediate in a previously reported synthesis of pentalenene.

引用

页码：5753 / 5756

页数：4

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