HEPATIC ULTRASTRUCTURE IN CONGENITAL TOTAL LIPODYSTROPHY WITH SPECIAL REFERENCE TO PEROXISOMES

被引：11

作者：

DECRAEMER, D ^{[1
]}

VANMALDERGEM, L ^{[1
]}

ROELS, F ^{[1
]}

机构：

[1] INST MORPHOL PATHOL, LOVERAL, BELGIUM

来源：

ULTRASTRUCTURAL PATHOLOGY | 1992年 / 16卷 / 03期

关键词：

LIPODYSTROPHY; MORPHOMETRY; PEROXISOME;

D O I：

10.3109/01913129209061360

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

The liver of an 8-year-old boy with congenital total lipodystrophy was investigated by means of catalase cytochemistry and morphometry. Comparison was made with eight human control livers. Light microscopy revealed cirrhosis and steatosis. Ultrastructural changes included lipid droplets with lamellae in the periphery, cup-shaped mitochondria, and nuclear pseudoinclusions. Peroxisomes were significantly increased in number but were not enlarged; they displayed various shapes and showed a moderate heterogeneity in catalase activity. A correlation between increased lipids and peroxisomal proliferation is suggested.

引用

页码：307 / 316

页数：10

共 37 条

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[2]

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