INHIBITION OF NADPH-CYTOCHROME P450 REDUCTASE BY CYCLOPHOSPHAMIDE AND ITS METABOLITES

被引：35

作者：

MARINELLO, AJ

BERRIGAN, MJ

STRUCK, RF

GUENGERICH, FP

GURTOO, HL

机构：

[1] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,DEPT EXPTL THERAPEUT,BUFFALO,NY 14263

[2] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,GRACE CANC DRUG CTR,BUFFALO,NY 14263

[3] SO RES INST,BIRMINGHAM,AL 35205

[4] VANDERBILT UNIV,DEPT BIOCHEM,NASHVILLE,TN 37232

[5] VANDERBILT UNIV,CTR ENVIRONM TOXICOL,NASHVILLE,TN 37232

来源：

关键词：

D O I：

10.1016/0006-291X(81)91759-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：399 / 406

页数：8

共 20 条

[1] PROTECTION BY N-ACETYLCYSTEINE OF CYCLOPHOSPHAMIDE METABOLISM-RELATED INVIVO DEPRESSION OF MIXED-FUNCTION OXYGENASE ACTIVITY AND INVITRO DENATURATION OF CYTOCHROME-P-450
BERRIGAN, MJ
GURTOO, HL
SHARMA, SD
STRUCK, RF
MARINELLO, AJ
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 93 (03) : 797 - 803
[2] COLVIN M, 1978, CLIN PHARM ANTINEOPL, P245
[3] COX PJ, 1976, CANCER TREAT REP, V60, P299
[4] EBEL RE, 1980, MICROSOMES DRUG OXID, V1, P315
[5] DESTRUCTION OF HEME AND HEMOPROTEINS MEDIATED BY LIVER MICROSOMAL REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE-CYTOCHROME P-450 REDUCTASE
GUENGERICH, FP
[J]. BIOCHEMISTRY, 1978, 17 (17) : 3633 - 3639
[6] GUENGERICH FP, ARCH BIOCH BIOPHYS
[7] GURTOO HL, 1976, CANCER TREAT REP, V60, P1285
[8] LAROS RK, 1971, J AMER MED ASSOC, V215, P445
[9] FUNCTIONAL ROLE OF THIOL-GROUPS IN PROTEASE-SOLUBILIZED NADPH-CYTOCHROME-C REDUCTASE FROM PORK-LIVER MICROSOMES
LAZAR, T
EHRIG, H
LUMPER, L
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 76 (02): : 365 - 371
[10] LOWRY OH, 1951, J BIOL CHEM, V193, P265