METHENAMINE-SILVER STAINING - A SIMPLE AND SENSITIVE STAINING METHOD FOR SENILE PLAQUES AND NEUROFIBRILLARY TANGLES

被引：11

作者：

HAGA, C ^{[1
]}

IKEDA, K ^{[1
]}

IWABUCHI, K ^{[1
]}

AKIYAMA, H ^{[1
]}

KONDOH, H ^{[1
]}

KOSAKA, K ^{[1
]}

机构：

[1] YOKOHAMA CITY UNIV,SCH MED,DEPT PSYCHIAT,YOKOHAMA 236,JAPAN

来源：

BIOTECHNIC & HISTOCHEMISTRY | 1994年 / 69卷 / 05期

关键词：

METHENAMINE-SILVER; ANTI-BETA PROTEIN; IMMUNOSTAINING; AMYLOID DEPOSITS; SENILE PLAQUES; DIFFUSE PLAQUES; ALZHEIMER-TYPE DEMENTIA; NEUROFIBRILLARY TANGLES;

D O I：

10.3109/10520299409106306

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An improved methenamine-silver impregnation method is presented which exhibits sensitivity for amyloid substances comparable to that of anti-beta protein immunostaining. In optimally treated sections, this technique stained both beta-amyloid deposits and neurofibrillary tangles, which are known to have a beta-pleated structure. This simple procedure allows a large number of sections to be stained for routine examination.

引用

页码：295 / 300

页数：6

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