SOMITE DIFFERENTIATION - SONIC SIGNALS SOMITES

被引:59
作者
BUMCROT, DA
MCMAHON, AP
机构
[1] Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0960-9822(95)00123-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Sonic hedgehog, a secreted signalling molecule known to play a role in the patterning of the central nervous system and the limb in vertebrates, also controls differentiation of the somites.
引用
收藏
页码:612 / 614
页数:3
相关论文
共 12 条
  • [1] Watterson, Fowler, Fowler, The role of the neural tube and notochord in development of the axial skeleton of the chick, Am J Anat, 95, pp. 337-399, (1954)
  • [2] Johnson, Laufer, Riddle, Tabin, Ectopic expression of Sonic hedgehog alters dorsal–ventral patterning of somites, Cell, 79, pp. 1165-1173, (1994)
  • [3] $$$, Lessier Lavigne, Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a Hedgehog homolog, Cell, 79, pp. 1175-1186, (1994)
  • [4] Fietz, Concordel, Barbosa, Johnson, Krauss, McMahon, Tabin, Ingham, The hedgehog gene family in Drosophila and vertebrate development, Development, Supplement, pp. 43-51, (1994)
  • [5] Pourquie, Coltey, Teillet, Ordahl, LeDouarin, Control of dorso-ventral patterning of somitic derivatives by notochord and floor plate, Proceedings of the National Academy of Sciences, 90, pp. 5242-5246, (1993)
  • [6] Dietrich, Schubert, Gruss, Altered Paxgene expressed in murine notochord mutants: the notochord is required to initiate and maintain ventral identity in the somite, Mech Dev, 44, pp. 189-207, (1993)
  • [7] Kuratani, Martin, Wawarsik, Lilly, Eichele, Olson, The expression pattern of the chick homeobox gene gMHox suggests a role in patterning of the limbs and face and in compartmentalization of somites, Dev Biol, 161, pp. 357-369, (1994)
  • [8] Munsterberg, Lassar, Combinatorial signals from the neural tube, floor plate and notochord induce myogenic bHLH gene expression in the somite, Development, 121, pp. 661-669, (1995)
  • [9] Lee, Ekker, von Kessler, Porter, Sun, Beachy, Autoproteoiysis in hedgehog protein biogenesis, Science, 266, pp. 1528-1537, (1994)
  • [10] Bumerot, Takada, McMahon, Proteolytic processing yields two secreted forms of Sonic hedgehog, Mol Cell Biol, 15, pp. 2294-2303, (1995)