WHAT IS WRONG WITH DOPAMINERGIC TRANSMISSION IN SCHIZOPHRENIA

被引：13

作者：

CROW, TJ

机构：

来源：

TRENDS IN NEUROSCIENCES | 1979年 / 2卷 / 02期

关键词：

D O I：

10.1016/0166-2236(79)90022-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this article, Tim Crow reviews the evidence that neuroleptic drugs exert their antipsychotic effects by blocking dopamine receptors. The results of a recent clinical study are entirely consistent with this theory and eliminate some other possibilities. Does this tell us anything about the disease process? Post-mortem neurochemical studies rule out a disturbance in the dopamine neurone itself, but focus sharply upon the state of the postsynaptic dopamine receptor. © 1979.

引用

页码：52 / 55

页数：4

共 18 条

[1] AMPHETAMINE PSYCHOSIS - BEHAVIORAL AND BIOCHEMICAL ASPECTS [J].

ANGRIST, B ;

SATHANANTHAN, G ;

WILK, S ;

GERSHON, S .

JOURNAL OF PSYCHIATRIC RESEARCH, 1974, 11 :13-23

[2]

BOWERS MB, 1974, ARCH GEN PSYCHIAT, V31, P50

[3]

CARENZI A, 1975, ARCH GEN PSYCHIAT, V32, P1055

[4]

CARLSSON A, 1963, ACTA PHARMACOL TOX, V20, P140

[5]

Connell PH, 1958, AMPHETAMINE PSYCHOSI

[6]

COTES M, PSYCHOL MED

[7] CATECHOLAMINE-CONTAINING NEURONS AND ELECTRICAL SELF-STIMULATION .1. REVIEW OF SOME DATA [J].

CROW, TJ .

PSYCHOLOGICAL MEDICINE, 1972, 2 (04) :414-&

[8]

GRIFFITH JD, 1972, ARCH GEN PSYCHIAT, V26, P97

[9]

JOHNSTONE EC, 1978, LANCET, V1, P848

[10]

KORNETSKY C, 1976, ARCH GEN PSYCHIAT, V33, P1425

← 1 2 →