ACUTE HEMORRHAGIC CONJUNCTIVITIS - SEROEPIDEMIOLOGY OF COXSACKIEVIRUS-A24 VARIANT AND ENTEROVIRUS-70 IN SINGAPORE

被引：22

作者：

GOH, KT ^{[1
]}

OOI, PL ^{[1
]}

MIYAMURA, K ^{[1
]}

OGINO, T ^{[1
]}

YAMAZAKI, S ^{[1
]}

机构：

[1] NATL INST HLTH,CENT VIRUS DIAGNOST LAB,TOKYO 141,JAPAN

来源：

JOURNAL OF MEDICAL VIROLOGY | 1990年 / 31卷 / 03期

关键词：

age distribution; epidemics; neutralising antibodies;

D O I：

10.1002/jmv.1890310313

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Epidemics of acute haemorrhagic conjunctivitis caused by a variant of coxsackievirus A24 (CA24v) and enterovirus 70 (EV70) have occurred periodically in Singapore. A seroepidemiological survey conducted before the CA24v epidemic in 1985 and in the midst of the EV70 epidemic in 1983 showed a neutralising antibody prevalence (⩾ 1:4) of 19.1% and 66.9% to CA24v and EV70, respectively. The seropositivity rate to both viruses was highest in children 10–14 years of age, but no sex or ethnic difference was noted. It appears from the data that an epidemic could be triggered when the herd immunity of the population falls below a critical level. There was a significant correlation in seroprevalence between CA24v and EV70 (P = 7.75 × 10−3). Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：245 / 247

页数：3

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