ALUMINUM UPTAKE BY THE PARATHYROID-GLANDS

被引：109

作者：

CANN, CE

PRUSSIN, SG

GORDAN, GS

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT MED, SAN FRANCISCO, CA 94143 USA

[2] UNIV CALIF BERKELEY, DEPT NUCL ENGN, BERKELEY, CA 94720 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1979年 / 49卷 / 04期

关键词：

D O I：

10.1210/jcem-49-4-543

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Al-containing drugs are used extensively to bind dietary phosphate and as antacids, but little is known about toxicity and tissue uptake of ingested Al. Al concentrations were measured by neutron activation analysis in tissues taken from hyperparathyroid and normal human subjects and from rats. The parathyroid glands contained significantly more Al per unit mass than did thyroid or cervical muscle. The concentration of Al in the parathyroids appears to be linearly related to dietary Al intake.

引用

页码：543 / 545

页数：3

共 8 条

[1] DIALYSIS ENCEPHALOPATHY SYNDROME - POSSIBLE ALUMINUM INTOXICATION
ALFREY, AC
LEGENDRE, GR
KAEHNY, WD
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1976, 294 (04) : 184 - 188
[2] EFFECT OF VITAMIN D AND DIETARY CALCIUM ON PARATHYROID ACTIVITY
AU, WYW
RAISZ, LG
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1965, 209 (03): : 637 - &
[3] BERLYNE GM, 1970, LANCET, V2, P494
[4] CANN CE, 1976, DISS ABSTR INT B, V37, P154
[5] EFFECT OF ALUMINUM HYDROXIDE ON CALCIUM, PHOSPHORUS AND ALUMINUM BALANCES, SERUM PARATHYROID-HORMONE CONCENTRATION AND ALUMINUM CONTENT OF BONE IN PATIENTS WITH CHRONIC RENAL-FAILURE
CLARKSON, EM
CLEMENTS, VR
WOODHEAD, JS
BAILEY, RR
ORIORDAN, JL
HYNSON, WV
DEWARDEN.HE
EASTWOOD, JB
LUCK, VA
[J]. CLINICAL SCIENCE, 1972, 43 (04) : 519 - +
[6] ALUMINUM ABSORPTION AND DISTRIBUTION - EFFECT OF PARATHYROID-HORMONE
MAYOR, GH
KEISER, JA
MAKDANI, D
KU, PK
[J]. SCIENCE, 1977, 197 (4309) : 1187 - 1189
[7] RECKER RR, 1977, J LAB CLIN MED, V90, P810
[8] UNDERWOOD EJ, 1971, TRADE ELEMENTS HUMAN, P432

← 1 →