PHYSICAL ASSOCIATION BETWEEN NONHOMOLOGOUS CHROMOSOMES PRECEDES DISTRIBUTIVE DISJUNCTION IN YEAST

被引:44
作者
LOIDL, J
SCHERTHAN, H
KABACK, DB
机构
[1] UNIV KAISERLAUTERN,DIV HUMAN GENET & HUMAN BIOL,D-67653 KAISERSLAUTERN,GERMANY
[2] UNIV MED & DENT NEW JERSEY,NEW JERSEY MED SCH,DEPT MICROBIOL & MOLEC GENET,NEWARK,NJ 07103
关键词
MEIOSIS; CHROMOSOME PAIRING; SEGREGATION; SACCHAROMYCES-CEREVISIAE;
D O I
10.1073/pnas.91.1.331
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
During meiosis homologous chromosomes normally pair, undergo reciprocal recombination, and then segregate from each other. Distributive disjunction is the meiotic segregation that is observed in the absence of homologous recombination and can occur for both nonrecombinant homologous chromosomes and completely nonhomologous chromosomes. While the mechanism of distributive disjunction is not known, several models have been presented that either involve or are completely independent of interactions between the segregating chromosomes. In this report, we demonstrate that distributive disjunction in Saccharomyces cerevisiae is preceded by an interaction between nonhomologous chromosomes.
引用
收藏
页码:331 / 334
页数:4
相关论文
共 31 条
[1]   GENETIC-CONTROL OF MEIOSIS [J].
BAKER, BS ;
CARPENTER, ATC ;
ESPOSITO, MS ;
ESPOSITO, RE ;
SANDLER, L .
ANNUAL REVIEW OF GENETICS, 1976, 10 :53-134
[2]   DISTRIBUTIVE SEGREGATION - MOTORS IN THE POLAR WIND [J].
CARPENTER, ATC .
CELL, 1991, 64 (05) :885-890
[3]   AN ALTERNATIVE PATHWAY FOR MEIOTIC CHROMOSOME SEGREGATION IN YEAST [J].
DAWSON, DS ;
MURRAY, AW ;
SZOSTAK, JW .
SCIENCE, 1986, 234 (4777) :713-717
[4]   MEIOTIC CHROMOSOME DISTRIBUTION IN DROSOPHILA OOCYTES - ROLES OF 2 KINESIN-RELATED PROTEINS [J].
ENDOW, SA .
CHROMOSOMA, 1992, 102 (01) :1-8
[5]   SYNAPSIS, DESYNAPSIS, AND FORMATION OF POLYCOMPLEX-LIKE AGGREGATES IN MALE MEIOSIS OF PALES-FERRUGINEA (DIPTERA, TIPULIDAE) [J].
FUGE, H .
CHROMOSOMA, 1979, 70 (03) :353-373
[6]  
GOLDWAY M, 1993, GENETICS, V133, P159
[7]  
Grell R. F., 1976, GENET BIOL DROSOPHIL, VIa, P435
[9]  
GUACCI V, 1991, GENETICS, V127, P475
[10]  
HAWLEY RS, 1980, GENETICS, V94, P625