LIVER-ENZYME CONCENTRATIONS AS MEASURE OF POSSIBLE INFECTIVITY IN CHRONIC ASYMPTOMATIC CARRIERS OF HEPATITIS-B

被引：12

作者：

BARBARA, JAJ ^{[1
]}

MIJOVIC, V ^{[1
]}

CLEGHORN, TE ^{[1
]}

TEDDER, RS ^{[1
]}

BRIGGS, M ^{[1
]}

机构：

[1] MIDDLESEX HOSP,SCH MED,DEPT VIROL,LONDON W1P 7LD,ENGLAND

来源：

BRITISH MEDICAL JOURNAL | 1978年 / 2卷 / 6152期

关键词：

D O I：

10.1136/bmj.2.6152.1600

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fifty-two British-born blood donors who were chronic carriers of hepatitis B surface antigen (HBsAg) were tested for the presence of hepatitis B e antigen (HBeAg) and antibody to HBeAg by an immunoradiometric assay. The presence of HBeAg was closely associated with a slight rise in serum liver enzyme concentrations, a high HBsAg titre, and male sex. We suggest that the finding of persistently raised serum liver enzyme concentrations in an asymptomatic HBsAg carrier might be useful as a likely indicator of HBeAg and high infectivity. © 1978, British Medical Journal Publishing Group. All rights reserved.

引用

页码：1600 / 1602

页数：3

共 17 条

[1] SEX DISTRIBUTION OF AUSTRALIA ANTIGEN
BLUMBERG, BS
SUTNICK, AI
LONDON, WT
MELARTIN, L
[J]. ARCHIVES OF INTERNAL MEDICINE, 1972, 130 (02) : 227 - +
[2] TRANSMISSION OF HBSAG FROM MOTHER TO INFANT IN 4 ETHNIC-GROUPS
DERSO, A
BOXALL, EH
TARLOW, MJ
FLEWETT, TH
[J]. BRITISH MEDICAL JOURNAL, 1978, 1 (6118) : 949 - 952
[3] HEATHCOT.J, 1974, LANCET, V1, P71
[4] HEATHCOT.J, 1974, LANCET, V2, P370
[5] IWARSON S, 1978, VOX SANG, V34, P311
[6] MAGNIUS LO, 1972, J IMMUNOL, V109, P1017
[7] MAGNIUS LO, 1975, JAMA-J AM MED ASSOC, V231, P356
[8] RELATION OF E-ANTIGEN TO HEPATITIS-B VIRUS-INFECTION IN AN AREA OF HYPERENDEMICITY
MAYNARD, JE
BARRETT, DH
MURPHY, BL
BRADLEY, DW
BERQUIST, KR
BENDER, TR
[J]. JOURNAL OF INFECTIOUS DISEASES, 1976, 133 (03) : 339 - 342
[9] EQUAL SUSCEPTIBILITY OF MALES AND FEMALES ON SANTA CRUZ ISLAND TO CARRIER STATE OF HEPATITIS-B SURFACE ANTIGEN
MAZZUR, S
JONES, N
[J]. JOURNAL OF INFECTIOUS DISEASES, 1976, 133 (03) : 331 - 333
[10] PREVALENCE OF HEPATITIS-B E-ANTIGEN AND ITS ANTIBODY AS DETECTED BY RADIOIMMUNOASSAYS
MUSHAHWAR, IK
OVERBY, LR
FROSNER, G
DEINHARDT, F
LING, CM
[J]. JOURNAL OF MEDICAL VIROLOGY, 1978, 2 (02) : 77 - 87

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