URINARY D-GLUCARIC ACID - AN INDEX OF HEPATIC MICROSOMAL ENZYME ACTIVITY IN HUMAN FEMALES

被引：27

作者：

FAHIM, MS

HALL, DG

FAHIM, Z

机构：

[1] Department of Obstetrics and Gynecology, University of Missouri School of Medicine Columbia, MO

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1969年 / 105卷 / 01期

关键词：

D O I：

10.1016/0002-9378(69)90170-7

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The administration of phenobarbital, a known hepatic microsomal enzyme induction agent, to human females causes a significant increase in urinary D-glucaric acid. Similar increases occur following administration of progesterone. These observations indicate that urinary glucaric acid reflects hepatic metabolic function and can be used as an index of microsomal enzyme activity in the human female. © 1969.

引用

页码：124 / &

共 9 条

[1] EVIDENCE FOR FUNCTION OF D-GLUCARIC ACID AS AN INDICATOR FOR DRUG INDUCED ENHANCED METABOLISM THROUGH GLUCURONIC ACID PATHWAY IN MAN [J].