ALTERNATING CISPLATINUM AND VAC INEFFECTIVE IN END STAGE SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK

被引：9

作者：

SIODLAK, MZ ^{[1
]}

STELL, PM ^{[1
]}

WILSON, JA ^{[1
]}

GREEN, JA ^{[1
]}

ALLISON, RS ^{[1
]}

ADLER, D ^{[1
]}

SQUADRELLISARACENO, M ^{[1
]}

机构：

[1] ROYAL LIVERPOOL HOSP,PRESCOT ST,POB 147,LIVERPOOL L69 3BX,ENGLAND

来源：

JOURNAL OF LARYNGOLOGY AND OTOLOGY | 1990年 / 104卷 / 08期

关键词：

D O I：

10.1017/S0022215100113441

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Sixteen patients with end stage squamous cell carcinoma of the head and neck were admitted to a phase II study of alternating courses of cisplatinum (100 mg/m2) and VAC (vincristine 1.4 mg/m2, adriamycin 50 mg/m2, cyclophosphamide 750 mg/m2) given at three weekly intervals. Only two patients achieved a response (12 per cent). The median survival time was 62 days which is much the same as that of a similar group of patients who received no chemotherapy in a previous trial (70 days). © 1990, JLO (1984) Limited. All rights reserved.

引用

页码：631 / 633

页数：3

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