VALIDITY AND INTERPRETATION OF BLOOD LEAD LEVELS - A STUDY OF DANISH SCHOOL-CHILDREN

Blood lead concentrations were measured in a group of children from a group of 9- to 10-year-old school children in Aarhus, Denmark. The study group was selected as a high-level and a low-level lead group, as identified by the lead concentration in the circumpulpal dentine in deciduous teeth shed 2-3 years previously. The validity of the blood sampling technique was investigated in adult volunteers, and lead was determined by electrothermal atomic absorption. Capillary blood sampling by a finger-stick method was preferred, as the slight contamination caused by this technique was deemed acceptable. The children with the highest dentine lead levels (n=70), had blood lead concentrations of 0.08-0.63 μmol/1 and a geometric mean of 0.28 μmol/1. The children with lowest dentine levels (n=76) had blood lead concentrations of 0.08-0.70 μmol/1 and a geometric mean of 0.18 μmol/l. The blood lead concentrations were compared with interview data on behaviour, family habits, diet, parents' tobacco smoking and occupation, water lead measurements, and traffic counts. A total of 20% of the variation in blood lead was explained by parents' tobacco smoking, the child's number in the sibship, gender, and consumption of canned food at home. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.