FOLLICULAR ASPIRATION DOES NOT PROTECT AGAINST THE DEVELOPMENT OF OVARIAN HYPERSTIMULATION SYNDROME

被引:28
作者
ABOULGHAR, MA
MANSOUR, RT
SEROUR, GI
ELATTAR, I
AMIN, Y
机构
[1] Obstetrics and Gynaecology Department, Cairo University, Cairo
[2] The Egyptian IVF-ET Center, Maadi, Cairo
[3] Obstetrics and Gynaecology Department, Al Azhar University, Cairo
[4] Bio-statistics Department, Cairo University, Cairo
关键词
OVARIAN HYPERSTIMULATION SYNDROME; FOLLICULAR ASPIRATION; GONADOTROPIN RELEASING HORMONE AGONIST ANALOG;
D O I
10.1007/BF01203820
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Objective: The purpose of this study was to determine the effect of follicular aspiration on the incidence of ovarian hyperstimulation syndrome (OHSS). Design: A retrospective study was done on 219 IVF cycles that proceeded to follicular aspiration (group A) and they were compared with 189 cycles of ovulation induction for non-IVF cycles (group B). We compared the incidence of OHSS in regularly ovulating patients (subgroups A1 and B1) and anovulatory patients (subgroups A2 and B2) in both groups. Settings: The study took place at The Egyptian IVF-ET Center. Participants: Participants were 319 infertility patients. Intervention: Ovulation was induced and follicles were aspirated. Main Outcome Measures: The incidences of moderate and severe OHSS were the main outcome measures. Results: The incidence of OHSS in group B was significantly higher than that in group A (P = 0.016). There was no significant difference in the incidence of OHSS between subgroup A1 and subgroup B1 or between subgroup A2 and subgroup B2. Conclusions: Follicular aspiration had no effect on the incidence of OHSS. In contrast, the higher incidence of OHSS in group B was related to the higher incidence of anovulatory infertility.
引用
收藏
页码:238 / 245
页数:8
相关论文
共 23 条
  • [1] Porter R.N., Smith W., Craft I.L., Abdulwhid N.A., Jacobs H.S., Induction of ovulation for in vitro fertilization using Buserelin and gonadotropins, Lancet, 2, pp. 1284-1285, (1984)
  • [2] Fleming R., Haxton M.J., Hamilton M.P.R., McCune G.S., Black W.P., Macnaughton M.C., Coutts J.R.T., Successful treatment of infertile women with oligomenorrhea using a combination of an LH-RH agonist and exogenous gonadotropins, BJOG: An International Journal of Obstetrics and Gynaecology, 92, pp. 369-374, (1985)
  • [3] Aboulghar M.A., Mansour R.T., Serour G.I., Successful treatment of long term unexplained infertility with gonadotropin-releasing hormone agonist analogue and human menopausal gonadotropin, Acta Obstet Gynecol Scand, 69, pp. 313-315, (1990)
  • [4] Golan A., Ron-El R., Herman A., Weinraub Z., Soffer Y., Caspi E., Ovarian hyperstimulation syndrome following D-Trp-6 luteinizing hormone-releasing hormone microcapsules and menotropins for in vitro fertilization, Fertil Steril, 50, pp. 912-916, (1988)
  • [5] Caspi E., Ron-El R., Golan A., Naechum H., Herman A., Soffer Y., Weinraub Z., Results of in vitro fertilization and embryo transfer by combined long-acting gonadotropin-releasing hormone analog D-Trp-6-luteinizing hormone-releasing hormone and gonadotropins, Fertil Steril, 51, pp. 95-99, (1989)
  • [6] Forman R.G., Frydman R., Egan D., Ross C., Barlow D., Severe ovarian hyperstimulation syndrome using agonists of gonadotropin-releasing hormone for in vitro fertilization: A European series and a proposal for prevention, Fertil Steril, 53, pp. 502-509, (1990)
  • [7] Golan A., Ron-El R., Herman A., Soffer Y., Weinraub Z., Caspi E., Ovarian hyperstimulation syndrome: An update review, Obstet Gynecol Surv, 44, pp. 430-439, (1989)
  • [8] Belaisch-Allart J., Belaisch J., Hazout A., Testart J., Frydman R., Selective oocyte retrieval: A new approach to ovarian hyperstimulation, Fertil Steril, 50, pp. 654-656, (1988)
  • [9] Rabau E., Serr D.M., David A., Human menopausal gonadotropins for anovulation and sterility, Am J Obstet Gynecol, 96, pp. 92-98, (1967)
  • [10] Schenker J.G., Weinstein D., Ovarian hyperstimulation syndrome: A current survey, Fertil Steril, 30, pp. 255-268, (1978)