NEUROFIBROMATOSIS TYPE-1 IN CHILDHOOD - CORRELATION OF MRI FINDINGS WITH INTELLIGENCE

被引：38

作者：

LEGIUS, E

DESCHEEMAEKER, MJ

STEYAERT, J

SPAEPEN, A

VLIETINCK, R

CASAER, P

DEMAEREL, P

FRYNS, JP

机构：

[1] UNIV HOSP GASTHUISBERG, DEPT CHILD PSYCHIAT, B-3000 LOUVAIN, BELGIUM

[2] UNIV HOSP GASTHUISBERG, DEPT PEDIAT, B-3000 LOUVAIN, BELGIUM

[3] UNIV HOSP GASTHUISBERG, DEPT RADIOL, B-3000 LOUVAIN, BELGIUM

[4] DEPT CLIN GENET, MAASTRICHT, NETHERLANDS

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1995年 / 59卷 / 06期

关键词：

NEUROFIBROMATOSIS TYPE 1; MAGNETIC RESONANCE IMAGING; INTELLIGENCE; HIGH INTENSITY LESIONS; BRAIN;

D O I：

10.1136/jnnp.59.6.638

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In a group of 28 children with neurofibromatosis type 1 aged between 4 and 16 years, neuroradiological findings were correlated with intelligence as measured by the Wechsler scales. The presence or specific location in the brain of T2 weighted prolonged signals on MRI was not associated with cognitive problems. No other physical characteristics associated with neurofibromatosis type 1 were found to correlate significantly with IQ. At the present these T2 weighted hyperintense spots should not be used to predict neurofibromatosis type 1 associated cognitive problems.

引用

页码：638 / 640

页数：3