INTERFERON IN THE PREVENTION OF GENITAL HERPES RECURRENCE

被引：12

作者：

ERON, LJ

HARVEY, L

TOY, C

SANTOMAURO, D

机构：

[1] SCHERING CORP, KENILWORTH, NJ 07033 USA

[2] FAIRFAX HOSP, DIV INFECT DIS, FALLS CHURCH, VA 22046 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1986年 / 30卷 / 04期

关键词：

D O I：

10.1128/AAC.30.4.608

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Patients with genital herpes were treated three times weekly for 12 weeks with 3 .times. 106 IU of alpha2b interferon (20 patients) or placebo (17 patients) administered by subcutaneous injection in a double-blind trial. Interferon had minimal effects on the suppression of recurrences and moderate toxicity (chills, fever, fatigue, and leukopenia), suggesting that this route and dosage of interferon may not be clinically useful for this indication.

引用

页码：608 / 610

页数：3

共 11 条

[1] GENITAL HERPES-SIMPLEX VIRUS-INFECTIONS - CLINICAL MANIFESTATIONS, COURSE, AND COMPLICATIONS
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[7] PARADOXICAL EFFECTS OF INTERFERON ON REACTIVATION OF ORAL INFECTION WITH HERPES-SIMPLEX VIRUS AFTER MICROVASCULAR DECOMPRESSION FOR TRIGEMINAL NEURALGIA
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