WHAT IS THE TRUE CLINICAL-SIGNIFICANCE OF PLASMA-PROTEIN BINDING DISPLACEMENT INTERACTIONS

[1] Sellers E.M., Plasma protein displacement interactions are rarely of clinical significance, Pharmacology, 18, (1979)

[2] Rowland M., Tozer T., Clinical pharmacokinetics. Concepts and applications, (1989)

[3] Gibaldi M., Biopharmaceutics and clinical pharmacokinetics, (1991)

[4] Svensson C.K., Woodruff M.N., Lalka D., Influence of protein binding and use of unbound (free) drug concentrations, Applied pharmacokinetics. Principles of therapeutic drug monitoring, pp. 187-219, (1986)

[5] Stockley I.H., Drug interactions: a source book of adverse interactions, their mechanisms, clinical importance and management, (1981)

[6] Hansten P.D., Drug interactions: clinical significance of drug interactions, (1985)

[7] Prescott L.F., Clinically important drug interactions, Drug treatment, (1987)

[8] MacKichan J.J., Protein binding displacement interactions. Fact or fiction?, Clin Pharmacokinet, 16, pp. 65-73, (1989)

[9] du Souich P., Verges J., Erill S., Plasma protein binding and pharmacological response, Clin Pharmacokinet, 24, (1993)

[10] Rolan P.E., Plasma protein binding displacement interactions — why are they still regarded as clinically important?, Br J Clin Pharmacol, 37, (1994)

[1] Sellers E.M., Plasma protein displacement interactions are rarely of clinical significance, Pharmacology, 18, (1979)

[2] Rowland M., Tozer T., Clinical pharmacokinetics. Concepts and applications, (1989)

[3] Gibaldi M., Biopharmaceutics and clinical pharmacokinetics, (1991)

[4] Svensson C.K., Woodruff M.N., Lalka D., Influence of protein binding and use of unbound (free) drug concentrations, Applied pharmacokinetics. Principles of therapeutic drug monitoring, pp. 187-219, (1986)

[5] Stockley I.H., Drug interactions: a source book of adverse interactions, their mechanisms, clinical importance and management, (1981)

[6] Hansten P.D., Drug interactions: clinical significance of drug interactions, (1985)

[7] Prescott L.F., Clinically important drug interactions, Drug treatment, (1987)

[8] MacKichan J.J., Protein binding displacement interactions. Fact or fiction?, Clin Pharmacokinet, 16, pp. 65-73, (1989)

[9] du Souich P., Verges J., Erill S., Plasma protein binding and pharmacological response, Clin Pharmacokinet, 24, (1993)

[10] Rolan P.E., Plasma protein binding displacement interactions — why are they still regarded as clinically important?, Br J Clin Pharmacol, 37, (1994)