AN IMPROVED SYNTHESIS OF N-ACETYLNEURAMINIC ACID

被引：22

作者：

HOW, MJ

HALFORD, MDA

STACEY, M

VICKERS, E

机构：

[1] Department of Chemistry, The University, Edgbaston

[2] Koch-Light Laboratories, Colnbrook,, Bucks Bucks

来源：

CARBOHYDRATE RESEARCH | 1969年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0008-6215(00)80572-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The overall yield and stereoselectivity of the aldol condensation reactions of 2-acetamido-2-deoxy-D-glucose and 2-acetamido-2-deoxy-D-mannose with oxal-acetate at pH 10 are improved by the incorporation of borate ion in the reaction mixture. Borate ion inhibits the alkaline epimerisation of various 2-acylamino-2-deoxyaldoses. © 1969.

引用

页码：313 / &

共 15 条

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[J]. JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (12) : 4022 - +
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