FORMATION OF RIBOSOME-G FACTOR-GDP COMPLEX IN PRESENCE OF FUSIDIC ACID

被引:134
作者
BODLEY, JW
ZIEVE, FJ
LIN, L
ZIEVE, ST
机构
[1] Department of Biochemistry, University of Minnesota Medical School, Radioisotope Service, Minneapolis
关键词
D O I
10.1016/0006-291X(69)90934-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
When ribosomes are incubated with G factor and GTP, a ribosome-G factor-GDP complex is formed. Fusidic acid does not inhibit the formation of this complex; in fact, more complex is isolated in the presence of the antibiotic (10-3 M) than in its absence. No complex containing GTP is detectable in the presence or absence of the antibiotic. © 1969.
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页码:437 / &
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