AFFINITY OF ATROPINE FOR MUSCARINE RECEPTORS IN HUMAN SPHINCTER PUPILLAE

被引：10

作者：

KAUMANN, AJ ^{[1
]}

HENNEKES, R ^{[1
]}

机构：

[1] UNIV DUSSELDORF,AUGEN KLIN,D-4000 DUSSELDORF 1,FED REP GER

来源：

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 1979年 / 306卷 / 03期

关键词：

Atropine; Carbachol; Isolated human iris; Muscarine receptor;

D O I：

10.1007/BF00507105

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Concentration-dependent contractions in response to carbachol were determined on isolated pieces of human iris. Atropine competitively antagonized the effect of carbachol. An apparent dissociation equilibrium constant of 0.4-0.7 nM was estimated for the muscarine receptor-atropine complex. © 1979 Springer-Verlag.

引用

页码：209 / 211

页数：3

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