THE MAJOR HISTOCOMPATIBILITY COMPLEX AND HUMAN-EVOLUTION

被引：55

作者：

KLEIN, J

GUTKNECHT, J

FISCHER, N

机构：

[1] UNIV TUBINGEN, INST BIOL 1, W-7400 TUBINGEN 1, GERMANY

[2] UNIV MIAMI, SCH MED, DEPT MICROBIOL & IMMUNOL, MIAMI, FL 33101 USA

来源：

TRENDS IN GENETICS | 1990年 / 6卷 / 01期

关键词：

D O I：

10.1016/0168-9525(90)90042-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Many alleles at the human major histocompatibility complex (HLA) loci diverged before the divergence of humans and great apes from a common ancestor. This fact puts a lower limit on the size of the bottleneck in human evolution: the genus Homo must have been founded by no less than ten and probably by more than 10 000 individuals. © 1990.

引用

页码：7 / 11

页数：5

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