GLYCOSIDASES IN SERUM OF CYSTIC-FIBROSIS PATIENTS

被引：10

作者：

CASOLA, L

DIMATTEO, G

ROMANO, M

RUTIGLIANO, B

MASTELLA, G

机构：

[1] CNR, INT INST GENET & BIOPHYS, VIA MARCONI 10, I-80125 NAPOLI, ITALY

[2] CHILDRENS HOSP ALESSANDRI, CYST FIBROSIS CLIN, VERONA, ITALY

来源：

CLINICA CHIMICA ACTA | 1979年 / 94卷 / 01期

关键词：

D O I：

10.1016/0009-8981(79)90188-8

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

In a study of 9 glycosidases [.gamma.-mannosidase, .gamma.-L-fucosidase, .beta.-n-acetylglucosaminidase, .beta.-n-acetylqalactoseaminidase, .beta.-glucuronidase, .beta.-galactosidase, .alpha.-glucosidase, arylsulfatase and acid phosphatase] in serum samples from 72 cystic fibrosis (CF) patients, 85 CF parents and 34 healthy and diseased controls, significant elevations of mean .alpha.-glucosidase levels were found in CF patients. No other glycosidases showed any significant change. Mean .alpha.-glucosidase levels in obligate heterozygotes were the same as in control individuals. .alpha.-Glucosidase levels in CF patients correlated with the degree of clinical impairment as measured by the Schwachman score.

引用

页码：83 / 88

页数：6

共 31 条

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