ENZYMATIC DIAGNOSIS OF NONKETOTIC HYPERGLYCINEMIA WITH LYMPHOBLASTS

被引：38

作者：

KURE, S ^{[1
]}

NARISAWA, K ^{[1
]}

TADA, K ^{[1
]}

机构：

[1] TOHOKU UNIV, SCH MED, DEPT PEDIAT, SENDAI, MIYAGI 980, JAPAN

来源：

JOURNAL OF PEDIATRICS | 1992年 / 120卷 / 01期

关键词：

D O I：

10.1016/S0022-3476(05)80610-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We developed a new enzymatic assay for the glycine cleavage system that used Epstein-Barr virus-transformed lymphoblasts instead of liver biopsy specimens. Patients with nonketotic hyperglycinemia from a deficiency of P-protein could be clearly distinguished from control subjects by activities in their lymphoblasts, suggesting the clinical usefulness of this method.

引用

页码：95 / 98

页数：4

共 18 条

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