TRANSARTERIAL INTERNAL RADIATION-THERAPY WITH I-131 LIPIODOL FOR MULTIFOCAL HEPATOCELLULAR-CARCINOMA - IMMEDIATE AND LONG-TERM RESULTS

被引：11

作者：

KAJIYA, Y

KOBAYASHI, H

NAKAJO, M

机构：

[1] Department of Radiology, Faculty of Medicine, Kagoshima University, Kagoshima, 890, 8-35-1 Sakuragaoka, Kagoshima-shi

来源：

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY | 1993年 / 16卷 / 03期

关键词：

I-131; LIPIODOL; TRANSARTERIAL INTERNAL RADIATION THERAPY; HEPATIC CANCER; CDDP (CIS-DIAMMINEDICHLOROPLATINUM); ADMOS (ADRIAMYCIN MITOMYCIN-C OIL SUSPENSION); CHEMOEMBOLIZATION;

D O I：

10.1007/BF02641884

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Transarterial internal radiation with I-131 Lipiodol (TAIR) was performed in 21 patients with multifocal hepatic carcinoma. Eight patients were treated by TAIR alone and 13 by combination of TAIR and intraarterial infusion of cis-diamminedichloroplatinum (CDDP) and/or adriamycin mitomycin C oil suspension (ADMOS). TAIR was found effective immediately and long-term. Serum alpha-fetoprotein (AFP) levels dropped to 50% or less in 7 of 14 patients. Eleven of 21 patients (52%) showed 50% or greater decrease in tumor size. The overall 1-year survival rate was 43% and 67% in patients who received 50 Gy or greater tumor dose. Lipiodol distribution pattern of the tumor indicated some difference in the prognosis between the scattered pattern and solid pattern. The solid pattern showed a statistically significant better survival rate. Patients treated with TAIR alone versus those treated with TAIR and chemotherapy showed no difference in their survival rate.

引用

页码：150 / 157

页数：8

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