ACYLPHOSPHONATES .7. A NEW METHOD FOR STEREOSPECIFIC AND STEREOSELECTIVE GENERATION OF DIDEOXYRIBONUCLEOSIDE PHOSPHOROTHIOATES VIA THE ACYLPHOSPHONATE INTERMEDIATES

被引：30

作者：

FUJII, M ^{[1
]}

OZAKI, K ^{[1
]}

SEKINE, M ^{[1
]}

HATA, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT LIFE CHEM,MIDORI KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON | 1987年 / 43卷 / 15期

关键词：

D O I：

10.1016/S0040-4020(01)81630-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3395 / 3407

页数：13

共 18 条

[1] NUCLEOSIDE 3'-PHOSPHOTRIESTERS AS KEY INTERMEDIATES FOR OLIGORIBONUCLEOTIDE SYNTHESIS .4. NEW METHOD FOR REMOVAL OF 2,2,2-TRICHLOROETHYL GROUP AND P-31-NMR AS A NEW TOOL FOR ANALYSIS OF DEBLOCKING OF INTERNUCLEOTIDE PHOSPHATE PROTECTING GROUPS [J].

ADAMIAK, RW ;

BIALA, E ;

GRZESKOWIAK, K ;

KIERZEK, R ;

KRASZEWSKI, A ;

MARKIEWICZ, WT ;

STAWINSKI, J ;

WIEWIOROWSKI, M .

NUCLEIC ACIDS RESEARCH, 1977, 4 (07) :2321-2329

[2] STEREOCHEMICAL COURSE OF NUCLEOTIDYL TRANSFER CATALYZED BY BACTERIOPHAGE-T7 INDUCED DNA-POLYMERASE [J].

BRODY, RS ;

ADLER, S ;

MODRICH, P ;

STEC, WJ ;

LEZNIKOWSKI, ZJ ;

FREY, PA .

BIOCHEMISTRY, 1982, 21 (10) :2570-2572

[3]

BURGER BMJ, 1978, NUCLEIC ACIDS RES SP, V4, P43

[4] DIASTEREOMERS OF 5'-O-ADENOSYL 3'-O-URIDYL PHOSPHOROTHIOATE - CHEMICAL SYNTHESIS AND ENZYMATIC PROPERTIES [J].

BURGERS, PMJ ;

ECKSTEIN, F .

BIOCHEMISTRY, 1979, 18 (04) :592-596

[5] PHOSPHOROTHIOATE ANALOGS OF NUCLEOTIDES - TOOLS FOR THE INVESTIGATION OF BIOCHEMICAL PROCESSES [J].

ECKSTEIN, F .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1983, 22 (06) :423-439

[6] STEREOCHEMISTRY OF ENZYMATIC-REACTIONS OF PHOSPHATES [J].

FREY, PA .

TETRAHEDRON, 1982, 38 (11) :1541-1567

[7] ACYLPHOSPHONATES .6. REACTION-MECHANISM OF ZN/ME3SICL MEDIATED CONVERSION OF 2,2,2-TRICHLOROETHOXYCARBONYLPHOSPHONATES TO SILYL PHOSPHITES [J].

FUJII, M ;

OZAKI, K ;

KUME, A ;

SEKINE, M ;

HATA, T .

TETRAHEDRON LETTERS, 1986, 27 (29) :3365-3368

[8] ACYLPHOSPHONATES .4. SYNTHESIS OF DITHYMIDINE PHOSPHONATE - A NEW METHOD FOR GENERATION OF PHOSPHONATE FUNCTION VIA AROYLPHOSPHONATE INTERMEDIATES [J].

KUME, A ;

FUJII, M ;

SEKINE, M ;

HATA, T .

JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (12) :2139-2143

[9] HIGHLY EFFICIENT CHEMICAL SYNTHESIS OF RP AND SP ADENYL(3'-5')ADENYL-0,0-PHOSPHOROTHIOATE [J].

MARLIER, JF ;

BENKOVIC, SJ .

TETRAHEDRON LETTERS, 1980, 21 (12) :1121-1124

[10]

MIKOLAJCZYK M, 1969, J CHEM SOC CHEM COMM, P1221

← 1 2 →