SELECTIVE INACTIVATION OF VITAMIN-B12 IN RATS BY NITROUS-OXIDE

被引：181

作者：

DEACON, R ^{[1
]}

LUMB, M ^{[1
]}

CHANARIN, I ^{[1
]}

PERRY, J ^{[1
]}

MINTY, B ^{[1
]}

HALSEY, MJ ^{[1
]}

NUNN, JF ^{[1
]}

机构：

[1] NORTHWICK PK HOSP, CLIN RES CTR, DIV ANAESTHESIA, HARROW HA1 3UJ, MIDDLESEX, ENGLAND

来源：

LANCET | 1978年 / 2卷 / 8098期

关键词：

D O I：

10.1016/S0140-6736(78)92341-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exposure of rats to nitrous oxide rapidly inactivated the cytosol enzyme, methionine synthetase, but the mitochondrial enzyme, methylmalonyl CoA mutase, seemed to be unaffected, although both enzymes require vitamin B12. © 1978.

引用

页码：1023 / 1024

页数：2

共 8 条

[1] AMESS JAL, 1978, LANCET, V2, P339
[2] REACTIONS OF GASES IN SOLUTION .3. SOME REACTIONS OF NITROUS OXIDE WITH TRANSITION-METAL COMPLEXES
BANKS, RGS
HENDERSON, RJ
PRATT, JM
[J]. JOURNAL OF THE CHEMICAL SOCIETY A -INORGANIC PHYSICAL THEORETICAL, 1968, (12): : 2886 - +
[3] MEASUREMENT OF URINARY METHYLMALONIC ACID BY A COMBINATION OF THIN-LAYER AND GAS CHROMATOGRAPHY
GOMPERTZ, D
[J]. CLINICA CHIMICA ACTA, 1968, 19 (03) : 477 - +
[4] REGULATION OF 5-METHYLTETRAHYDROFOLATE - HOMOCYSTEINE METHYLTRANSFERASE ACTIVITY BY METHIONINE, VITAMIN-B12, AND FOLATE IN CULTURED BABY HAMSTER KIDNEY-CELLS
KAMELY, D
LITTLEFIELD, JW
ERBE, RW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (09) : 2585 - 2589
[5] LASSEN HCA, 1956, LANCET, V270, P527
[6] EFFECT OF VITAMIN-B12 INHIBITION INVIVO - IMPAIRED FOLATE POLYGLUTAMATE BIOSYNTHESIS INDICATING THAT "5-METHYLTETRAHYDROPTEROYL-GLUTAMATE IS NOT ITS USUAL SUBSTRATE
MCGING, P
REED, B
WEIR, DG
SCOTT, JM
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 82 (02) : 540 - 546
[7] FETO-TOXICITY IN RATS FOLLOWING CHRONIC EXPOSURE TO HALOTHANE, NITROUS-OXIDE, OR METHOXYFLURANE
POPE, WDB
HALSEY, MJ
LANSDOWN, ABG
SIMMONDS, A
BATEMAN, PE
[J]. ANESTHESIOLOGY, 1978, 48 (01) : 11 - 16
[8] ETHANOLAMINE AMMONIA-LYASE - INACTIVATION OF HOLOENZYME BY N2O AND MECHANISM OF ACTION OF COENZYME B12
SCHRAUZER, GN
STADLBAUER, EA
[J]. BIOINORGANIC CHEMISTRY, 1975, 4 (03): : 185 - 198

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