RELIABLE AND FACILE METHOD FOR PREPARATION OF SOLVENTLESS BILAYER LIPID-MEMBRANES FOR ELECTROANALYTICAL INVESTIGATIONS

被引：46

作者：

NIKOLELIS, DP ^{[1
]}

KRULL, UJ ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT CHEM,CHEM SENSORS GRP,ERINDALE CAMPUS,3359 MISSISSAUGA RD N,MISSISSAUGA L5L 1C6,ONTARIO,CANADA

来源：

TALANTA | 1992年 / 39卷 / 08期

关键词：

D O I：

10.1016/0039-9140(92)80293-M

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Bilayer lipid membranes continue to be of interest as elements for development and investigation of chemically-modified electrodes and biosensors, yet also continue to be difficult to prepare and replicate with precision. A simplified and reliable technique for the rapid formation of solventless bilayer lipid membranes is described, and the method has been shown to produce membranes which nominally vary by only 5-10% with respect to ion conductivity. Methods for rapid physical and chemical characterization of these membranes for establishment of reproducibility and quality are given.

引用

页码：1045 / 1049

页数：5

共 11 条

[1] ELECTRICAL CAPACITY OF BLACK LIPID FILMS AND OF LIPID BILAYERS MADE FROM MONOLAYERS [J].