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CYTOKINE RECEPTOR SIGNALING

被引：1104
作者：
IHLE, JN
机构：
[1] Department of Biochemistry, St Jude Children’s Research Hospital, Memphis, TN, 38101-0318, 332 North Lauderdale
来源：
NATURE | 1995年 / 377卷 / 6550期
关键词：
D O I：
10.1038/377591a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Many cell functions are regulated by members of the cytokine receptor superfamily. Signalling by these receptors depends upon their association with Janus kinases (JAKs), which couple ligand binding to tyrosine phosphorylation of signalling proteins recruited to the receptor complex. Among these are the signal transducers and activators of transcription (STATs), a family of transcription factors that contribute to the diversity of cytokine responses.
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页码：591 / 594
页数：4
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