RENIN INHIBITORS - DIPEPTIDE ANALOGS OF ANGIOTENSINOGEN INCORPORATING TRANSITION-STATE, NONPEPTIDIC REPLACEMENTS AT THE SCISSILE BOND

被引：47

作者：

BOLIS, G ^{[1
]}

FUNG, AKL ^{[1
]}

GREER, J ^{[1
]}

KLEINERT, HD ^{[1
]}

MARCOTTE, PA ^{[1
]}

PERUN, TJ ^{[1
]}

PLATTNER, JJ ^{[1
]}

STEIN, HH ^{[1
]}

机构：

[1] ABBOTT LABS, DIV CARDIOVASC RES, ABBOTT PK, IL 60064 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 10期

关键词：

D O I：

10.1021/jm00393a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1729 / 1737

页数：9

共 34 条

[1] BANGHAM DR, 1975, CLIN SCI MOL MED, V48, pS135
[2] STATINE-CONTAINING RENIN INHIBITOR - DISSOCIATION OF BLOOD-PRESSURE LOWERING AND RENIN INHIBITION IN SODIUM-DEFICIENT DOGS
BLAINE, EH
SCHORN, TW
BOGER, J
[J]. HYPERTENSION, 1984, 6 (02) : I111 - I118
[3] RENIN INHIBITORS - SYNTHESES OF SUBNANOMOLAR, COMPETITIVE, TRANSITION-STATE ANALOG INHIBITORS CONTAINING A NOVEL ANALOG OF STATINE
BOGER, J
PAYNE, LS
PERLOW, DS
LOHR, NS
POE, M
BLAINE, EH
ULM, EH
SCHORN, TW
LAMONT, BI
LIN, TY
KAWAI, M
RICH, DH
VEBER, DF
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (12) : 1779 - 1790
[4] ENKEPHALIN SYNTHESIS OF 2 PENTAPEPTIDES ISOLATED FROM PORCINE BRAIN WITH RECEPTOR-MEDIATED OPIATE AGONIST ACTIVITY
BOWER, JD
GUEST, KP
MORGAN, BA
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (23): : 2488 - 2492
[5] SELECTIVE REDUCTIONS .21. 9-BORABICYCLO[3.3.1]NONANE IN TETRAHYDROFURAN AS A NEW SELECTIVE REDUCING AGENT IN ORGANIC-SYNTHESIS - REACTION WITH SELECTED ORGANIC-COMPOUNDS CONTAINING REPRESENTATIVE FUNCTIONAL-GROUPS
BROWN, HC
KRISHNAMURTHY, S
YOON, NM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (10) : 1778 - 1791
[6] SYNTHESIS OF OXAZOLIDIN-2-ONES USING CARBONATE ION ON A POLYMERIC SUPPORT
CARDILLO, G
ORENA, M
SANDRI, S
TOMASINI, C
[J]. TETRAHEDRON, 1985, 41 (01) : 163 - 167
[7] PARTIALLY MODIFIED RETRO-INVERSO PEPTIDES - COMPARATIVE CURTIUS REARRANGEMENTS TO PREPARE 1,1-DIAMINOALKANE DERIVATIVES
CHOREV, M
GOODMAN, M
[J]. INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1983, 21 (03): : 258 - 268
[8] THE DIRECT CONVERSION OF STEROIDAL DELTA-5-3-BETA-ALCOHOLS TO DELTA-5-KETONES AND DELTA-4-3-KETONES
DJERASSI, C
ENGLE, RR
BOWERS, A
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1956, 21 (12) : 1547 - 1548
[9] PURIFICATION OF HUMAN RENIN SUBSTRATE
DORER, FE
LENTZ, KE
KAHN, JR
LEVINE, M
SKEGGS, LT
[J]. ANALYTICAL BIOCHEMISTRY, 1978, 87 (01) : 11 - 18
[10] SIGNIFICANCE OF THE VASCULAR RENIN-ANGIOTENSIN PATHWAY
DZAU, VJ
[J]. HYPERTENSION, 1986, 8 (07) : 553 - 559

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