STRUCTURE-ACTIVITY RELATIONSHIP STUDIES ON 4''-ORTHO-ACYLTYLOSIN DERIVATIVES - SIGNIFICANCE OF THEIR 23-ORTHO-MYCINOSYL AND 4''-ORTHO-ACYL MOIETIES IN ANTIMICROBIAL ACTIVITY AGAINST MACROLIDE-RESISTANT MICROBES

被引：8

作者：

KIYOSHIMA, K ^{[1
]}

SAKAMOTO, M ^{[1
]}

NOMURA, H ^{[1
]}

YOSHIOKA, T ^{[1
]}

OKAMOTO, R ^{[1
]}

SAWA, T ^{[1
]}

NAGANAWA, H ^{[1
]}

TAKEUCHI, T ^{[1
]}

机构：

[1] INST MICROBIAL CHEM,SHINAGAWA KU,TOKYO 141,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1989年 / 42卷 / 11期

关键词：

D O I：

10.7164/antibiotics.42.1661

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1661 / 1672

页数：12

共 13 条

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[4] KIYOSHIMA K, 1989, CHEM PHARM BULL, V37, P861
[5] MITSUHASHI S, 1984, ANTIMICROBIAL DRUG R, P279
[6] NEW MACROLIDE ANTIBIOTICS PRODUCED BY MUTANTS FROM STREPTOMYCES-FRADIAE NRRL-2702
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[7] PHYSICOCHEMICAL PROPERTIES OF NEW ACYL DERIVATIVES OF TYLOSIN PRODUCED BY MICROBIAL TRANSFORMATION
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[J]. JOURNAL OF ANTIBIOTICS, 1980, 33 (11) : 1300 - 1308
[8] BIOLOGICAL PROPERTIES OF NEW ACYL DERIVATIVES OF TYLOSIN
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[9] CHEMICAL AND BIOLOGICAL STUDIES ON 16-MEMBERED MACROLIDE ANTIBIOTICS
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[10] 4''-O-(4-METHOXYPHENYL)-ACETYLTYLOSIN, A NEW MACROLIDE DERIVATIVE OF THERAPEUTIC IMPORTANCE
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SAWA, T
NAGANAWA, H
HAMADA, M
UMEZAWA, H
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IGUCHI, H
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ISHIKURA, T
[J]. JOURNAL OF ANTIBIOTICS, 1987, 40 (09) : 1358 - 1360

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