INVIVO DEGRADATION OF COLLAGEN VICRYL MATERIALS IN RABBIT EAR CHAMBERS

被引：7

作者：

BIRD, IN

SILVER, IA

GORHAM, SD

FRENCH, DA

机构：

[1] Department of Pathology, School of Medical Sciences, Bristol

[2] Devro Ltd, Moodiesburn, Chryston, Glasgow

[3] Ethicon Ltd, Bankhead Ave, Sighthill Industrial Estate, Edinburgh

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1991年 / 2卷 / 01期

关键词：

D O I：

10.1007/BF00701685

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The in vivo breakdown of collagen-vicryl composites (types 9 and 12) was followed in rabbit ear chambers over a period of 5 weeks. In this time the implants were incorporated into the granulation tissue growing in the chambers. Materials that were sterilized by gamma irradiation were resorbed faster than those sterilized with ethylene oxide or disinfected with alcohol, which suggests that irradiation weakened the material. Histological observation revealed that the collagen component had disappeared from all the composites by day 35 and the surrounding tissue showed a mild foreign-body reaction.

引用

页码：36 / 42

页数：7

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