THE INDUCTION OF ADIPOSE CONVERSION IN 3T3-L1 CELLS IS ASSOCIATED WITH EARLY PHOSPHORYLATION OF A 60-KDA NUCLEAR-PROTEIN

被引:5
作者
BRANDES, R
ARAD, R
BARTANA, J
机构
[1] Department of Biochemistry, Hebrew University, Hadassah Medical School, Jerusalem, 91010
关键词
ADIPOSE CONVERSION; HYPOLIPIDEMIC FIBRATE; IMBX; CAMP; PROTEIN PHOSPHORYLATION;
D O I
10.1016/0014-5793(91)80725-I
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The induction of adipose conversion in 3T3-L1 cells by bezafibrate has been shown to be enhanced by dibutyryl-cAMP. We here report that the induction of adipose conversion in 3T3-L1 cells, by either benzafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60-kDa acidic protein found in the nuclear fraction.
引用
收藏
页码:63 / 65
页数:3
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