THE HIGHLY CONSERVED DEFENDER AGAINST THE DEATH-1 (DAD1) GENE MAPS TO HUMAN-CHROMOSOME-14Q11-Q12 AND MOUSE CHROMOSOME-14 AND HAS PLANT AND NEMATODE HOMOLOGS

被引：33

作者：

APTE, SS

MATTEI, MG

SELDIN, MF

OLSEN, BR

机构：

[1] GRP HOSP TIMONE,HOP ENFANTS,INSERM,U406,F-13385 MARSEILLE 5,FRANCE

[2] DUKE UNIV,SCH MED,DEPT MED,DURHAM,NC 27710

[3] DUKE UNIV,SCH MED,DEPT MICROBIOL,DURHAM,NC 27710

来源：

FEBS LETTERS | 1995年 / 363卷 / 03期

关键词：

CELL DEATH; APOPTOSIS; PROGRAMMED CELL DEATH; CHROMOSOME; 14; DAD1;

D O I：

10.1016/0014-5793(95)00321-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have cloned the cDNA encoding the mouse DAD1 (defender against apoptotic cell death) protein, While showing an expected high homology with the previously cloned human and Xenopus DAD1-encoding cDNAs, this sequence has striking homology to partial cDNA sequences reported from O, sativa (rice) and C, elegans (nematode), suggesting the existence of plant and invertebrate homologs of this highly conserved gene, The human and mouse DAD1 genes map to chromosome 14q11-q12 and chromosome 14, respectively, This mapping data supports and extends the previously reported similarities between human chromosome 14q and mouse chromosome 14.

引用

页码：304 / 306

页数：3

共 17 条

[1] BASIC LOCAL ALIGNMENT SEARCH TOOL
ALTSCHUL, SF
GISH, W
MILLER, W
MYERS, EW
LIPMAN, DJ
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) : 403 - 410
[2] BISHOP D T, 1985, Genetic Epidemiology, V2, P349, DOI 10.1002/gepi.1370020404
[3] COX DW, 1993, HUMAN GENE MAPPING C, P575
[4] Green EL, 1981, GENETICS PROBABILITY, P77
[5] AUTOSOMAL-DOMINANT FAMILIAL SPASTIC PARAPLEGIA IS GENETICALLY HETEROGENEOUS AND ONE LOCUS MAPS TO CHROMOSOME-14Q
HAZAN, J
LAMY, C
MELKI, J
MUNNICH, A
DERECONDO, J
WEISSENBACH, J
[J]. NATURE GENETICS, 1993, 5 (02) : 163 - 167
[6] GENETIC-MAPPING OF DNA TOPOISOMERASE-I-RELATED SEQUENCES TO MOUSE CHROMOSOME-2 AND CHROMOSOME-14
KINGSMORE, SF
LO, CK
HWANG, J
HUI, CF
SELDIN, MF
[J]. MAMMALIAN GENOME, 1994, 5 (04) : 247 - 248
[7] DNA PROBE LOCALIZATION AT 18P113 BAND BY INSITU HYBRIDIZATION AND IDENTIFICATION OF A SMALL SUPERNUMERARY CHROMOSOME
MATTEI, MG
PHILIP, N
PASSAGE, E
MOISAN, JP
MANDEL, JL
MATTEI, JF
[J]. HUMAN GENETICS, 1985, 69 (03) : 268 - 271
[8] MOUSE CHROMOSOME-14
NADEAU, JH
MCCARTHY, L
COX, R
[J]. MAMMALIAN GENOME, 1993, 4 : S203 - S210
[9] MOLECULAR-CLONING OF A HUMAN CDNA-ENCODING A NOVEL PROTEIN, DAD1, WHOSE DEFECT CAUSES APOPTOTIC CELL-DEATH IN HAMSTER BHK-21-CELLS
NAKASHIMA, T
SEKIGUCHI, T
KURAOKA, A
FUKUSHIMA, K
SHIBATA, Y
KOMIYAMA, S
NISHIMOTO, T
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (10) : 6367 - 6374
[10] EXPRESSION OF THE BACULOVIRUS P35-GENE INHIBITS MAMMALIAN NEURAL CELL-DEATH
RABIZADEH, S
LACOUNT, DJ
FRIESEN, PD
BREDESEN, DE
[J]. JOURNAL OF NEUROCHEMISTRY, 1993, 61 (06) : 2318 - 2321

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